It contains oestrogen-like withanolides for anti-osteoporotic activity. The proteasome inhibition, osteoblastogenesis, suppressed osteoclast differentiation are by inhibiting osteoclastogenesis.
It improves trabecular micro-architecture of the long bones, increases biomechanical strength parameters of the vertebra and femur. It decreases bone turnover markers (osteocalcin and TNFα) and expression of skeletal osteoclastogenic genes. It also increases new bone formation and expression of osteogenic genes in the femur bone
It exerts a bone-protective effect by increasing bone mineral density. This activity may be at least partially attributable to an increase in serum DHEA levels and a Ca2+-sparing effect
It is well known for its bone remineralization properties. The observed effect is due to presence of tannins, Saponins and triterpenoids content which have definite action on bone regeneration and calcium, phosphorus and alkaline phosphate metabolism which plays important role in osteoblastic activity
Recommended Dosage & Direction:
2 capsule twice a day with Milk or as directed by the physician
Indications: Osteoporosis, Calcium Deficiency
Presentation: 60 capsule bottle